In order for the mass to accelerate up the incline, the external force Fs must be sufficient to combat the effects of gravity as well as friction, which is proportional to the coefficient of friction, µ. Steeper inclines require more external force, as do more abrasive ones. The surface gravity g is an unchanging parameter on the surface of our planet, which is related to its mass and radius. Note that the Fs term is divided by m, which means that in addition to fighting gravity and friction, the external force is fighting the inertia of the block itself.
I encourage you to take a moment, and look carefully at the challenges that are present in your life. Will you muster up the Fs to overcome them? Will you minimize your m, allow yourself to make progress? What represents your g, µ, and θ? I'll wait right here while you look into that.